TLR4 /MD2 Complex antibody (PE-Cy7)

Catalog No. ABIN2659608

This Rat Monoclonal antibody specifically detects in FACS. It exhibits reactivity toward Mouse.

Quick Overview for TLR4 /MD2 Complex antibody (PE-Cy7) (ABIN2659608)

Target: TLR4 /MD2 Complex

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: PE-Cy7

Application: Flow Cytometry (FACS)

Clone: MTS510

Product Details

Purification: The antibody was purified by affinity chromatography, and conjugated with PE/Cy7 under optimal conditions. The solution is free of unconjugated PE/Cy7 and unconjugated antibody.

Isotype: IgG2a kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.2 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from prolonged exposure to light. Do not freeze.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C.

Target Details

Target: TLR4 /MD2 Complex

Background: Toll-like receptors are highly conserved from Drosophila to humans and share structural and functional similarities. They are type I transmembrane signaling receptors which activate the innate immune system in response to pathogen invasion. So far, at least 13 TLR members have been identified. The secretory protein, MD2, associates with cell-surface bound TLR4 (CD284) on monocytes, B cells and T cells. TLR4 has been recognized as critical for host recognition of bacterial LPS in conjunction with MD2.