CD1c antibody (PE/Dazzle™ 594)

Catalog No. ABIN2659687

The Mouse Monoclonal anti-CD1c antibody has been validated for FACS. It is suitable to detect CD1c in samples from Human.

Quick Overview for CD1c antibody (PE/Dazzle™ 594) (ABIN2659687)

Target: CD1c (CD1C) (T-cell surface glycoprotein CD1c (CD1C))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD1c antibody is conjugated to PE/Dazzle™ 594

Application: Flow Cytometry (FACS)

Clone: L161

Product Details anti-CD1c Antibody (PE/Dazzle™ 594)

Purification: The antibody was purified by affinity chromatography and conjugated with PE/Dazzle™ 594 under optimal conditions. The solution is free of unconjugated PE/Dazzle™ 594 and unconjugated antibody.

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from prolonged exposure to light. Do not freeze.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C.

Target Details for CD1c

Target: CD1c (CD1C) (T-cell surface glycoprotein CD1c (CD1C))

Alternative Name: CD1c

Background: CD1c, also known as R7 or M241, is a 43 kD member of the five CD1 antigens (CD1a-e) in humans. The CD1 Molecules are type I glycoprotein with structural similarities to MHC class I and are non-covalently associated with β2-microglobulin, belonging to the Ig superfamily. CD1c is expressed on cortical thymocytes, Langerhans cells, dendritic cells, and a subset of B cells. It has been reported that CD1c is also expressed on mature T cells in a tightly regulated manner. CD1c is involved in antigen-presentation of glycolipids. It may also act in T cells as an immune regulatory molecule.