PD-1 antibody (Biotin)

Catalog No. ABIN2661307

The Biotin-conjugated Rat Monoclonal anti-PD-1 antibody (Clone RMP1-30) (ABIN2661307) specifically detects PD-1 in WB, IP and ELISA (Capture). The antibody is reactive with Mouse samples.

Quick Overview for PD-1 antibody (Biotin) (ABIN2661307)

Target: PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This PD-1 antibody is conjugated to Biotin

Application: Western Blotting (WB), Immunoprecipitation (IP), ELISA (Capture)

Clone: RMP1-30

Product Details anti-PD-1 Antibody (Biotin)

Purification: The antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions. The solution is free of unconjugated biotin.

Isotype: IgG2b kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C.

Target Details for PD-1

Target: PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

Alternative Name: CD279

Background: CD279 is a 50-55 kD immunoglobulin superfamily member also known as programmed death-1 (PD-1). PD-1 is expressed on a subset of CD4-CD8- thymocytes and on activated T and B cells. PD-1 is thought to be involved in lymphocyte clonal selection and peripheral tolerance. The PD-1 ligands, PD-L1 (also known as B7-H1) and PD-L2 (B7-DC), are members of the B7 immunoglobulin superfamily.

Pathways: Cancer Immune Checkpoints