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CD45RO antibody (FITC)

This Mouse Monoclonal antibody specifically detects CD45RO in FACS. It exhibits reactivity toward Human.
Catalog No. ABIN2661744

Quick Overview for CD45RO antibody (FITC) (ABIN2661744)

Target

CD45RO

Reactivity

  • 77
  • 14
  • 14
  • 14
  • 12
  • 2
  • 2
Human

Host

  • 66
  • 13
Mouse

Clonality

  • 67
  • 12
Monoclonal

Conjugate

  • 14
  • 6
  • 5
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This CD45RO antibody is conjugated to FITC

Application

  • 63
  • 28
  • 20
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  • 2
  • 1
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Flow Cytometry (FACS)

Clone

UCHL1
  • Cross-Reactivity

    Chimpanzee, Marmoset

    Purification

    The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions. The solution is free of unconjugated FITC.

    Isotype

    IgG2a kappa
  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Concentration

    0.5 mg/mL

    Buffer

    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handling Advice

    Protect from prolonged exposure to light. Do not freeze.

    Storage

    4 °C

    Storage Comment

    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Target

    CD45RO

    Alternative Name

    CD45RO

    Background

    CD45RO is a 180 kD single chain membrane glycoprotein. It is a splice variant of tyrosine phosphatase CD45, lacking the A, B, and C determinants. The CD45RO isoform is expressed on activated and memory T cells, some B cell subsets, activated monocytes/macrophages, and granulocytes. CD45RO enhances both T cell receptor and B cell receptor signaling mediated activation. CD45 and its isoforms non-covalently associate with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4. CD45 has also been reported to bind galectin-1 and CD22. CD45 isoform expression can change in response to cytokines.
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