ITGA6 antibody (FITC)

Catalog No. ABIN2661762

This Rat Monoclonal antibody specifically detects ITGA6 in FACS and CyTOF. It exhibits reactivity toward Human and Mouse.

Quick Overview for ITGA6 antibody (FITC) (ABIN2661762)

Target: ITGA6 (Integrin, alpha 6 (ITGA6))

Reactivity: Human, Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This ITGA6 antibody is conjugated to FITC

Application: Flow Cytometry (FACS), Cytometry by Time of Flight (CyTOF)

Clone: GoH3

Product Details anti-ITGA6 Antibody (FITC)

Cross-Reactivity: Baboon, Cynomolgus, Rhesus Monkey, Horse (Equine), Cow (Bovine), Sheep (Ovine), Pig (Porcine), Dog (Canine), Cat (Feline), Rabbit, Capuchin Monkey, Chicken, Chimpanzee

Purification: The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions. The solution is free of unconjugated FITC.

Isotype: IgG2a kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from prolonged exposure to light. Do not freeze.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C.

Target Details for ITGA6

Target: ITGA6 (Integrin, alpha 6 (ITGA6))

Alternative Name: CD49f

Background: CD49f is a 120 kD integrin family member also known as VLA-6 α chain and α6 integrin subunit. CD49f associates with either integrin β1 (CD29) or integrin β4 (CD104) to form receptors (VLA-6 or α6β4 complex) for laminin and kalinin. CD49f is expressed on platelets, monocytes, T cells, placental trophoblasts, and epithelial and endothelial cells. CD49f is involved in adhesion and can act as a co-stimulatory molecule for T cell activation and proliferation.

Pathways: CXCR4-mediated Signaling Events, Brown Fat Cell Differentiation, Integrin Complex