CD1d antibody (Pacific Blue)

Catalog No. ABIN2662220

This anti-CD1d antibody is a Rat Monoclonal antibody detecting CD1d in FACS and IF. Suitable for Mouse.

Quick Overview for CD1d antibody (Pacific Blue) (ABIN2662220)

Target: CD1d (CD1D) (CD1d Molecule (CD1D))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This CD1d antibody is conjugated to Pacific Blue

Application: Flow Cytometry (FACS), Immunofluorescence (IF)

Clone: 1B1

Product Details anti-CD1d Antibody (Pacific Blue)

Purification: The antibody was purified by affinity chromatography, and conjugated with Pacific Blue™ under optimal conditions. The solution is free of unconjugated Pacific Blue™.

Isotype: IgG2b kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from prolonged exposure to light. Do not freeze.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C.

Target Details for CD1d

Target: CD1d (CD1D) (CD1d Molecule (CD1D))

Alternative Name: CD1d

Background: CD1d, known as CD1.1 and Ly-38, is a 48 kD type I membrane glycoprotein with structural similarities to MHC class I and is non-covalently associated with β2-microglobulin. In humans, CD1 family consists of group I proteins (CD1a, CD1b, and CD1c), group II (CD1d), and group III (CD1e). But CD1d is the only CD1 Molecule has been found in mouse. Mouse CD1d has broad tissue distribution, and is found on leukocytes, dendritic cells, epithelial cells, and thymocytes. CD1d plays a role in non-peptide glycolipid antigen presentation to CD1d-restricted T cells. It has been shown that PKCδ is a critical regulator of CD1d-mediated antigen presentation.

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process