SCARB1 antibody (PE)

Catalog No. ABIN2662621

The Mouse Monoclonal anti-SCARB1 antibody has been validated for WB, IHC, IF, IP and FACS. It is suitable to detect SCARB1 in samples from Human.

Quick Overview for SCARB1 antibody (PE) (ABIN2662621)

Target: SCARB1 (Scavenger Receptor Class B, Member 1 (SCARB1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SCARB1 antibody is conjugated to PE

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), Flow Cytometry (FACS)

Clone: M1B9

Product Details anti-SCARB1 Antibody (PE)

Purification: The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from prolonged exposure to light. Do not freeze.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C.

Target Details for SCARB1

Target: SCARB1 (Scavenger Receptor Class B, Member 1 (SCARB1))

Alternative Name: CD36L1

Background: Scavenger receptor class B type I (SCARB1), also known as CD36L1, is an integral membrane protein found in numerous cell types and tissues that is mainly expressed in the liver and the adrenal glands. Its primary function is facilitating the uptake of cholesteryl esters from high-density lipoproteins (HDL) due to its high affinity to HDL. This function serves to lower the risk of development of atherosclerosis. SCARB1 is also able to bind to other lipoproteins such as LDL, OxLDL, and VLDL. SCARB1 is also likely to be involved in pathogen recognition through its recognition of mycobacteria and other viral proteins and regulates vitamin E levels in the tissue.

Pathways: Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Lipid Metabolism, SARS-CoV-2 Protein Interactome