Acetylated Lysine antibody (acetylated) (PE)

Catalog No. ABIN2662804

The Mouse Monoclonal anti-Acetylated Lysine antibody has been validated for FACS. It is suitable to detect Acetylated Lysine in samples from .

Quick Overview for Acetylated Lysine antibody (acetylated) (PE) (ABIN2662804)

Target: Acetylated Lysine

Reactivity: Please inquire

Host: Mouse

Clonality: Monoclonal

Conjugate: This Acetylated Lysine antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Clone: 15G10

Product Details anti-Acetylated Lysine Antibody (PE)

Binding Specificity: acetylated

Purification: The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.

Isotype: IgG2b kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from prolonged exposure to light. Do not freeze.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C.

Target Details for Acetylated Lysine

Target: Acetylated Lysine

Target Type: Chemical

Background: Proteins are reversibly and dynamically acetylated on the ε-amino group of lysine by acetyltransferases and deacetylated by deacetylases. This post-translational modification can regulate protein function (interactions with other proteins and DNA binding). Histones and transcription factors (PCAF, p53, p300, etc) appear to be the major targets of acetyltransferases. Acetylation is usually associated with chromatin remodeling and transcriptional activation, although in some cases (telomeres) it is associated with gene silencing. The 15G10 antibody recognizes acetylated lysine residues on proteins.