T Cell Receptor (TCR) V beta 12 antibody (PE)

Catalog No. ABIN2662863

This Mouse Monoclonal antibody specifically detects T Cell Receptor (TCR) V beta 12 in FACS. It exhibits reactivity toward Mouse.

Quick Overview for T Cell Receptor (TCR) V beta 12 antibody (PE) (ABIN2662863)

Target: T Cell Receptor (TCR) V beta 12

Reactivity: Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: PE

Application: Flow Cytometry (FACS)

Clone: MR11-1

Product Details

Purification: The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.2 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from prolonged exposure to light. Do not freeze.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C.

Target Details

Target: T Cell Receptor (TCR) V beta 12

Alternative Name: TCR V Beta12

Background: T cell receptor Vβ12 (TCR Vβ12) is a variant of TCR β chain and, along with TCR α chain, forms the TCR heterodimer. In association with the CD3 complex, TCR α/β is responsible for antigen recognition through interaction with MHC-peptide complex to initiate the T cell-mediated immune responses. The MR11-1 antibody reacts with the Vβ 12 TCR of mice bearing the b haplotype. It has been reported that Mtv-8 and Mtv-9 cause clonally deletion of Vβ12+ T cells.