FR4 antibody (PE)

Catalog No. ABIN2663702

The PE-conjugated Rat Monoclonal anti-FR4 antibody (Clone TH6) (ABIN2663702) specifically detects FR4 in FACS, Act, CMCD, IF, IHC and WB. The antibody is reactive with Mouse samples.

Quick Overview for FR4 antibody (PE) (ABIN2663702)

Target: FR4

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: PE

Application: Flow Cytometry (FACS), Activation (Act), Complement Mediated Cell Depletion (CMCD), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)

Clone: TH6

Product Details

Cross-Reactivity (Details): Mouse Folate Receptor 4

Purification: The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.

Isotype: IgG2b kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.2 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from prolonged exposure to light. Do not freeze.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C.

Target Details

Target: FR4

Background: Folate receptor 4 (FR4) is a surface receptor for folic acid (Vitamin B9).It was recently reported that FR4 is highly and constitutively expressed on mouse CD4+ CD25+ natural regulatory T cells (Treg).The high expression of this surface marker on Treg can be used in combination with CD4 and CD25 to distinguish Treg from other types of T cells.Since FR4 is a surface marker,this antibody may be used in combination with anti-CD4 and/or CD25 to sort living T reg cells for functional studies.