TRAFs and NIK-Associated Protein (TNAP) antibody (PE)
Quick Overview for TRAFs and NIK-Associated Protein (TNAP) antibody (PE) (ABIN2663937)
Target
See all TRAFs and NIK-Associated Protein (TNAP) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Characteristics
- The W8B2 antibody reacts with an antigen, TNAP (Tissue non-specific alkaline phosphatase), that is selectively expressed on bone marrow mesenchymal stem cells, but not on placenta-derived mesenchymal stem cells. It was previously reported that the antibody recognized MSCA-1, mesenchymal stem cell antigen-1. Mesenchymal stem cells or MSCs were originally named as bone marrow stromal cells. They are a population of adult stem cells with a large capacity for self-renewal and multipotency for differentiation into a variety of cell types including osteoblasts, chondrocytes, myocytes, adipocytes, β-pancreatic islets cells and certain neuronal cells. MSCs reside in many tissues, such as bone marrow, placenta, adipose tissue, adult peripheral blood, fetal blood, skin, as well as liver and lung. Besides their plasticity for tissue repair, MSCs also exhibit a powerful immunosuppressive activity and play important role in supporting hematopoiesis.
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Purification
- The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
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Isotype
- IgG1 kappa
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Buffer
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Protect from prolonged exposure to light. Do not freeze.
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Storage
- 4 °C
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Storage Comment
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- TRAFs and NIK-Associated Protein (TNAP)
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Alternative Name
- TNAP
Target
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