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ITGAL antibody

ITGAL Reactivity: Human ICFC Host: Mouse Monoclonal m24 unconjugated
Catalog No. ABIN2664157
  • Target See all ITGAL Antibodies
    ITGAL (Integrin alpha-L (ITGAL))
    Reactivity
    • 134
    • 66
    • 16
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 104
    • 54
    • 44
    • 1
    Mouse
    Clonality
    • 159
    • 43
    • 1
    Monoclonal
    Conjugate
    • 75
    • 27
    • 23
    • 18
    • 7
    • 6
    • 6
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ITGAL antibody is un-conjugated
    Application
    • 147
    • 43
    • 37
    • 33
    • 29
    • 29
    • 23
    • 18
    • 8
    • 6
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Intracellular Flow Cytometry (ICFC)
    Purification
    The antibody was purified by affinity chromatography.
    Clone
    M24
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product ITGAL Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Target
    ITGAL (Integrin alpha-L (ITGAL))
    Alternative Name
    CD11a/CD18 (ITGAL Products)
    Background
    CD11/CD18 belongs to the integrin family of proteins. It is heterodimeric cell surface receptor expressed on all leukocytes. CD18, in association with integrin α chain CD11a, CD11b, and CD11c forms LFA-1, Mac-1, and αXβ2, respectively, and plays an important role in leukocyte adhesion. CD11/CD18 complexes bind ICAM-1 (CD54), ICAM-2 (CD102), ICAM-3 (CD50), iC3b, and fibrinogen. Clone m24 binds the extended/open high affinity conformation of CD11a/CD18. The antibody can be used as a reporter of the activation state of the integrin receptor in response to exposure to Mg2+ or Mn2+.
    Pathways
    Activated T Cell Proliferation, Integrin Complex
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