CD38 antibody
Quick Overview for CD38 antibody (ABIN2664650)
Target
See all CD38 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Purification
- The antibody was purified by affinity chromatography.
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Isotype
- IgG2b kappa
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 0.5 mg/mL
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Buffer
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Storage Comment
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- CD38
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Background
- CD38 is a 45 kD type II transmembrane ADP-ribosyl cyclase expressed on early hematopoietic precursors and leukocytes, hepatic stellate cells, astrocytes and epithelial cells. CD38 expression can be upregulated upon cell activation. CD38 catalyzes the production of cyclic APD ribose, which is important in Ca2+ release. CD38 induces production of proinflammatory cytokines and proliferation. The ligand for CD38 is CD31. Impairment in CD38 expression is associated with immunological and behavioral disorders.
Target
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