DLL1 antibody

Catalog No. ABIN2664930

This Mouse Monoclonal antibody specifically detects DLL1 in FACS. It exhibits reactivity toward Human.

Quick Overview for DLL1 antibody (ABIN2664930)

Target: DLL1 (delta-Like 1 (DLL1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This DLL1 antibody is un-conjugated

Application: Flow Cytometry (FACS)

Clone: MHD1-314

Product Details anti-DLL1 Antibody

Purification: The antibody was purified by affinity chromatography.

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C.

Target Details for DLL1

Target: DLL1 (delta-Like 1 (DLL1))

Alternative Name: delta-Like Protein 1

Background: Delta-like protein 1 is a type I transmembrane protein. The mature form consist of an extracellular domain of 528 amino acids (aa) that contain a DSL domain and eight tandem EGF repeats, the transmembrane region is 23 aa long and has a 155 aa cytoplasmic domain. After the binding of Notch receptors, the extracellular and cytoplasmic domains are cleaved, and the later is translocated into the cell nucleus to regulate gene expression. Delta-like protein 1 is expressed in heart and pancreas and in a lower amount in brain and muscle. During fetal life, it is transiently expressed during gastrulation and early organogenesis and its expression remains through adult life in hematopoietic tissues and the cortico-medullary region of the thymus.

Pathways: Notch Signaling, Stem Cell Maintenance