GPR83 antibody

Catalog No. ABIN2665011

This Mouse Monoclonal antibody specifically detects GPR83 in FACS and ICFC. It exhibits reactivity toward Human.

Quick Overview for GPR83 antibody (ABIN2665011)

Target: GPR83 (G Protein-Coupled Receptor 83 (GPR83))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This GPR83 antibody is un-conjugated

Application: Flow Cytometry (FACS), Intracellular Flow Cytometry (ICFC)

Clone: K07JP05

Product Details anti-GPR83 Antibody

Purification: The antibody was purified by affinity chromatography.

Isotype: IgG2a kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C.

Target Details for GPR83

Target: GPR83 (G Protein-Coupled Receptor 83 (GPR83))

Alternative Name: GPR83

Background: GPR83, also known as GIR, is a seven-pass membrane protein that belongs to the G-protein coupled receptor 1 family. GPR83 is an orphan GPR homologous to tachykinin and neuropeptide Y (NPY) receptors. GPR83 is expressed in the brain and in both murine and human Treg cells. GPR83 is reported to regulate core body temperature and there are four isoforms of GPR83. Studies have suggested that isoform-4, but not isoform-1, is associated with the suppressive functions of Treg cells. The precise role of GPR83 in Treg function is unclear.