Pro-Major Basic Protein 1 antibody
This Mouse Monoclonal antibody specifically detects Pro-Major Basic Protein 1 in FACS. It exhibits reactivity toward Human.
Catalog No. ABIN2665341
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Quick Overview for Pro-Major Basic Protein 1 antibody (ABIN2665341)
Target
Pro-Major Basic Protein 1
Reactivity
Human
Host
Mouse
Clonality
Monoclonal
Application
Flow Cytometry (FACS)
Clone
J175-7D4
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Purification
- The antibody was purified by affinity chromatography.
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Isotype
- IgG1 kappa
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 0.5 mg/mL
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Buffer
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Storage Comment
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- Pro-Major Basic Protein 1
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Background
- Pro-form of Major Basic Protein 1 (ProMBP1) is composed of a strongly acidic 90-residue propart and a highly basic mature portion of 117 residues. It is an extensively and very heterogeneously glycosylated proteoglycan. ProMBP1 is processed to 14 kD MBP1 by convertase during maturation and localized in cell granule core. The mature MBP1 is a cytotoxic protein. The mAb J175-7D4 binds ProMBP1 and intermediate ProMBP1, but not mature MBP1. It specifically stain basophils, does not stain eosinophils, granulocytes, and mast cells and can be used as a marker for human basophils.
Target
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