TCR V Gamma1.1 + V Gamma1.2 antibody

Catalog No. ABIN2665404

This Armenian Hamster Monoclonal antibody specifically detects in ICFC. It exhibits reactivity toward Mouse.

Quick Overview for TCR V Gamma1.1 + V Gamma1.2 antibody (ABIN2665404)

Target: TCR V Gamma1.1 + V Gamma1.2

Reactivity: Mouse

Host: Armenian Hamster

Clonality: Monoclonal

Application: Intracellular Flow Cytometry (ICFC)

Clone: 4B2-9

Product Details

Purification: The antibody was purified by affinity chromatography.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C.

Target Details

Target: TCR V Gamma1.1 + V Gamma1.2

Background: In mice, the TCR g locus consists of seven Vg, four Jg and four Cg genes, which are differentially expressed through their lifespan. During fetal and early postnatal life, very few γ/δ T cells express TCR Vγ1.1 or Vγ 1.2 chains. In adult mice, however, a major fraction of the γ/δ T cell repertoire comprise either TCR Vγ1.1 or Vγ1.2 chains. The Vγ1.1 gene rearranges almost exclusively with the Jg4-Cg4 genes, while the Vγ1.2 gene preferentially does with Jg1.