LIN28A antibody

Catalog No. ABIN2666352

This Mouse Monoclonal antibody specifically detects LIN28A in FACS and BR. It exhibits reactivity toward Human.

Quick Overview for LIN28A antibody (ABIN2666352)

Target: LIN28A (Lin-28 Homolog A (C. Elegans) (LIN28A))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This LIN28A antibody is un-conjugated

Application: Flow Cytometry (FACS), Blocking Reagent (BR)

Clone: 14E6-4E6

Product Details anti-LIN28A Antibody

Purification: The antibody was purified by affinity chromatography.

Isotype: IgG2a, IgG2a kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Upon receipt, store undiluted between 2°C and 8°C.

Target Details for LIN28A

Target: LIN28A (Lin-28 Homolog A (C. Elegans) (LIN28A))

Alternative Name: Lin28A

Background: LIN28A is a highly conserved RNA-binding protein and reprogramming factor that plays important roles in development, self-renewal of stem cells, glucose metabolism and tumorigenesis. Lin28A modulates not only miRNAs, particularly the let-7 family miRNAs, but also the translation of mRNAs that are important for cell growth and metabolism. LIN28A/B has been observed to be overexpressed in a wide range of solid tumors and hematological malignancies, and has emerged as a new therapeutic target candidate for cancer.

Pathways: Stem Cell Maintenance