T and B cell Activation Marker antibody (Pacific Blue)

Catalog No. ABIN2667331

The Rat Monoclonal anti- antibody has been validated for FACS and CyTOF. It is suitable to detect in samples from Human and Mouse.

Quick Overview for T and B cell Activation Marker antibody (Pacific Blue) (ABIN2667331)

Target: T and B cell Activation Marker

Reactivity: Human, Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: Pacific Blue

Application: Flow Cytometry (FACS), Cytometry by Time of Flight (CyTOF)

Clone: GL7

Product Details

Characteristics: The GL7 antigen, also known as Ly77, is a 35 kD protein. The GL7 antigen has an epitope containing non-sulfated α 2-6-sialyl-LacNAc recognized by the GL7 antibody. The GL7 antigen is expressed by pre-B and immature B cells, activated T and B cells, and about 20 % of TCR-bright thymocytes. It is upregulated on mouse splenocytes following activation. It may play a role in regulation or adhesion. GL7 high-expressing B cells show higher antibody production and antigen presenting capacity.

Purification: The antibody was purified by affinity chromatography and conjugated with Pacific Blue™ under optimal conditions. The solution is free of unconjugated Pacific Blue™.

Isotype: IgM kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from prolonged exposure to light. Do not freeze.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C.

Target Details

Target: T and B cell Activation Marker