Histone H2A antibody (AA 1-5)

Catalog No. ABIN2668298

This anti-Histone H2A antibody is a Rabbit Polyclonal antibody detecting Histone H2A in WB. Suitable for Human. This Primary Antibody has been cited in 4+ publications.

Quick Overview for Histone H2A antibody (AA 1-5) (ABIN2668298)

Target: Histone H2A

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Histone H2A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Histone H2A Antibody

Binding Specificity: AA 1-5

Purification: Affinity Purified

Immunogen: This Histone H2A antibody was raised against a mixture of synthetic peptides corresponding to amino acid residues 1-5 and 81-96 of human Histone H2A.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 μg/μL

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice:

Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Storage: -80 °C

Storage Comment: Antibodies in solution can be stored at -80 °C for 2 years.

Expiry Date: 6 months

References for anti-Histone H2A antibody (ABIN2668298)

Hu, Li, Zhang, Zheng: "HSCARG, a novel regulator of H2A ubiquitination by downregulating PRC1 ubiquitin E3 ligase activity, is essential for cell proliferation." in: Nucleic acids research, Vol. 42, Issue 9, pp. 5582-93, (2014) (PubMed).

Li, Guan, Huang, Hu, Zheng: "RNF168-mediated H2A neddylation antagonizes ubiquitylation of H2A and regulates DNA damage repair." in: Journal of cell science, Vol. 127, Issue Pt 10, pp. 2238-48, (2014) (PubMed).

Li, Corsa, Pan, Wu, Ferguson, Yu, Min, Dou: "MOF and H4 K16 acetylation play important roles in DNA damage repair by modulating recruitment of DNA damage repair protein Mdc1." in: Molecular and cellular biology, Vol. 30, Issue 22, pp. 5335-47, (2010) (PubMed).

Bazzi, Mantiero, Trovesi, Lucchini, Longhese: "Dephosphorylation of gamma H2A by Glc7/protein phosphatase 1 promotes recovery from inhibition of DNA replication." in: Molecular and cellular biology, Vol. 30, Issue 1, pp. 131-45, (2009) (PubMed).

Target Details for Histone H2A

Target: Histone H2A

Molecular Weight: 14 kDa

Gene ID: 92815