TET2 antibody (AA 1-300)

Catalog No. ABIN2668527

This Mouse Monoclonal antibody specifically detects TET2 in WB and IP. It exhibits reactivity toward Human and has been mentioned in 2+ publications.

Quick Overview for TET2 antibody (AA 1-300) (ABIN2668527)

Target: TET2 (Tet Methylcytosine Dioxygenase 2 (TET2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TET2 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Clone: 21F11

Product Details anti-TET2 Antibody

Binding Specificity: AA 1-300

Purification: Protein A Chromatography

Immunogen: This antibody was raised against a recombinant protein corresponding to amino acids 1-300 of human Tet2.

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1 μg/μL

Buffer: Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice:

Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Storage: -20 °C

Storage Comment: Antibodies in solution can be stored at -20 °C for 2 years.

Expiry Date: 6 months

References for anti-TET2 antibody (ABIN2668527)

Wallner, Schröder, Leitão, Berulava, Haak, Beißer, Rahmann, Richter, Manke, Bönisch, Arrigoni, Fröhler, Klironomos, Chen, Rajewsky, Müller, Ebert, Lengauer, Barann, Rosenstiel, Gasparoni, Nordström et al.: "Epigenetic dynamics of monocyte-to-macrophage differentiation. ..." in: Epigenetics & chromatin, Vol. 9, pp. 33, (2016) (PubMed).

Gong, Guo, Niu, Jin, Zhang, Shi, Zhang, Li, Chen, Ma: "Epigenetic silencing of TET2 and TET3 induces an EMT-like process in melanoma." in: Oncotarget, Vol. 8, Issue 1, pp. 315-328, (2016) (PubMed).

Target Details for TET2

Target: TET2 (Tet Methylcytosine Dioxygenase 2 (TET2))

Alternative Name: Tet2

Molecular Weight: 220 kDa

Gene ID: 54790

Pathways: Warburg Effect