Histone H4 antibody (3meLys20)

Catalog No. ABIN2668855

The Mouse Monoclonal anti-Histone H4 antibody has been validated for WB, ChIP and DB. It is suitable to detect Histone H4 in samples from Human and Mouse. There are 3+ publications available.

Quick Overview for Histone H4 antibody (3meLys20) (ABIN2668855)

Target: Histone H4

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This Histone H4 antibody is un-conjugated

Application: Western Blotting (WB), Chromatin Immunoprecipitation (ChIP), Dot Blot (DB)

Clone: 6F8-D9

Product Details anti-Histone H4 Antibody

Binding Specificity: 3meLys20

Purification: Protein G Chromatography

Immunogen: This Histone H4 trimethylLys20 antibody (mAb) was raised against a peptide containing trimethylLys20 of Histone H4.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1 μg/μL

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice:

Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Storage: -20 °C

Storage Comment: Antibodies in solution can be stored at -20 °C for 2 years.

Expiry Date: 6 months

References for anti-Histone H4 antibody (ABIN2668855)

Gonzalez-Vasconcellos, Schneider, Anastasov, Alonso-Rodriguez, Sanli-Bonazzi, Fernández, Atkinson: "The Rb1 tumour suppressor gene modifies telomeric chromatin architecture by regulating TERRA expression." in: Scientific reports, Vol. 7, pp. 42056, (2017) (PubMed).

Dal-Pra, Hodgkinson, Mirotsou, Kirste, Dzau: "Demethylation of H3K27 Is Essential for the Induction of Direct Cardiac Reprogramming by miR Combo." in: Circulation research, Vol. 120, Issue 9, pp. 1403-1413, (2017) (PubMed).

Nelson, Jaber-Hijazi, Cole, Robertson, Pawlikowski, Norris, Criscione, Pchelintsev, Piscitello, Stong, Rai, McBryan, Otte, Nixon, Clark, Riethman, Wu, Schotta, Garcia, Neretti, Baird, Berger, Adams: "Mapping H4K20me3 onto the chromatin landscape of senescent cells indicates a function in control of cell senescence and tumor suppression through preservation of genetic and epigenetic stability." in: Genome biology, Vol. 17, Issue 1, pp. 158, (2016) (PubMed).

Target Details for Histone H4

Target: Histone H4

Molecular Weight: 8 kDa

Gene ID: 121504