Histone H4 antibody (acLys5)

Catalog No. ABIN2668876

There are 4+ publications for this product available. The Rabbit Polyclonal anti-Histone H4 antibody is suitable to detect Histone H4 in samples from Human. It has been validated for WB, IF, ICC, ChIP and DB.

Quick Overview for Histone H4 antibody (acLys5) (ABIN2668876)

Target: Histone H4 (HISTH4)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Histone H4 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Chromatin Immunoprecipitation (ChIP), Dot Blot (DB)

Product Details anti-Histone H4 Antibody

Binding Specificity: acLys5

Purification: None

Immunogen: This Histone H4 acetylLys5 antibody was raised against a peptide including acetyllysine 5 of histone H4.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice:

Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Storage: -20 °C

Storage Comment: Antibodies in solution can be stored at -20 °C for 2 years.

Expiry Date: 6 months

References for anti-Histone H4 antibody (ABIN2668876)

Valdez, Li, Murray, Ji, Liu, Popat, Champlin, Andersson: "Comparison of the cytotoxicity of cladribine and clofarabine when combined with fludarabine and busulfan in AML cells: Enhancement of cytotoxicity with epigenetic modulators." in: Experimental hematology, Vol. 43, Issue 6, pp. 448-61.e2, (2015) (PubMed).

Miao, Chen, Genuth, Paterson, Zhang, Wu, Li, Cleary, Riggs, Harlan, Lorenzi, Kolterman, Sun, Lachin, Natarajan: "Evaluating the role of epigenetic histone modifications in the metabolic memory of type 1 diabetes." in: Diabetes, Vol. 63, Issue 5, pp. 1748-62, (2014) (PubMed).

Larsson, Ulfhammer, Magnusson, Bergh, Lunke, El-Osta, Medcalf, Svensson, Karlsson, Jern: "Role of histone acetylation in the stimulatory effect of valproic acid on vascular endothelial tissue-type plasminogen activator expression." in: PLoS ONE, Vol. 7, Issue 2, pp. e31573, (2012) (PubMed).

Valdez, Murray, Nieto, Li, Wang, Champlin, Andersson: "Synergistic cytotoxicity of the DNA alkylating agent busulfan, nucleoside analogs and suberoylanilide hydroxamic acid in lymphoma cell lines." in: Leukemia & lymphoma, Vol. 53, Issue 5, pp. 973-81, (2012) (PubMed).

Target Details for Histone H4

Target: Histone H4 (HISTH4)

Alternative Name: Histone H4

Molecular Weight: 8 kDa

Gene ID: 121504