CD68 antibody (AA 42-155)

Catalog No. ABIN2682982

The Mouse Monoclonal anti-CD68 antibody has been validated for FACS, IHC, WB, ELISA and ICC. It is suitable to detect CD68 in samples from Human. There is 1 publication available.

Quick Overview for CD68 antibody (AA 42-155) (ABIN2682982)

Target: CD68 (CD68 Molecule (CD68))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD68 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunohistochemistry (IHC), Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Clone: 3F7D3

Product Details anti-CD68 Antibody

Binding Specificity: AA 42-155

Purpose: CD68 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human CD68 (AA: 42-155) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-CD68 antibody (ABIN2682982)

Peivandi, Martens, Heitplatz, Guseva, Mueller, Martens: "Industrial Processing Induces Pericardial Patch Degeneration." in: Frontiers in surgery, Vol. 9, pp. 881433, (2022) (PubMed).

Target Details for CD68

Target: CD68 (CD68 Molecule (CD68))

Alternative Name: CD68

Background: This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms.

Molecular Weight: 37.4 kDa

Gene ID: 968

UniProt: P34810