LAMP2 antibody

Catalog No. ABIN2688886

This anti-LAMP2 antibody is a Mouse Monoclonal antibody detecting LAMP2 in ICS. Suitable for Human. This Primary Antibody has been cited in 2+ publications.

Quick Overview for LAMP2 antibody (ABIN2688886)

Target: LAMP2 (Lysosomal-Associated Membrane Protein 2 (LAMP2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This LAMP2 antibody is un-conjugated

Application: Intracellular Staining (ICS)

Clone: H4B4

Product Details anti-LAMP2 Antibody

Brand: BD Pharmingen™

Characteristics: Reacts with the heavily glycosylated 120 kD lysosmal-associated protein, LAMP-2. LAMP-2 is a widely expressed intracellular antigen. It is also expressed on the surface of activated platelets, PHA-activated lymphocytes and some tumor cell lines, including U937 and KG1a. LAMP-2 has been shown to be a ligand for E-selectin-mediated cell adhesion. LAMP-1 (CD107a) and LAMP-2 are carriers for poly-N-acetyllactosamines, and are able to display sialyl Le[x] termini. Profile of intracellular staining of Jurkat cells fixed and permeabilized with Cytofix/Cytoperm (Cat. No. 554714) and analyzed on a FACScan

BD Pharmingen™ Purified Mouse Anti-Human CD107b - Purified - Clone H4B4 - Isotype Mouse IgG1, κ - Reactivity Hu - 0.1 mg

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store undiluted at 4°C.

References for anti-LAMP2 antibody (ABIN2688886)

Febbraio, Silverstein: "Identification and characterization of LAMP-1 as an activation-dependent platelet surface glycoprotein." in: The Journal of biological chemistry, Vol. 265, Issue 30, pp. 18531-7, (1990) (PubMed).

Chen, Cha, Yuksel, Gracy, August: "Isolation and sequencing of a cDNA clone encoding lysosomal membrane glycoprotein mouse LAMP-1. Sequence similarity to proteins bearing onco-differentiation antigens." in: The Journal of biological chemistry, Vol. 263, Issue 18, pp. 8754-8, (1988) (PubMed).

Target Details for LAMP2

Target: LAMP2 (Lysosomal-Associated Membrane Protein 2 (LAMP2))

Alternative Name: CD107b

Background: Synonyms: LAMP-2

Pathways: Autophagy