CD20 antibody

Catalog No. ABIN2689076

This Mouse Monoclonal antibody specifically detects CD20 in IHC (fro), IHC (f) and ICS. It exhibits reactivity toward Human.

Quick Overview for CD20 antibody (ABIN2689076)

Target: CD20 (MS4A1) (Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD20 antibody is un-conjugated

Application: Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Intracellular Staining (ICS)

Clone: H1

Product Details anti-CD20 Antibody

Brand: BD Pharmingen™

Characteristics: The H1(FB1) antibody reacts with a cytoplasmic domain of CD20, a 33-37- kDa tetraspan phosphoprotein that is expressed on B lymphocytes from the pre-B stage and most malignant B cells and is lost during plasma cell differentiation. Low level CD20 expression is observed on a subset of normal circulating T lymphocytes, and CD20-positive T-cell lymphomas have been reported. The CD20 Molecule is associated with membrane lipid raft domains, acts as a channel for calcium ions, and is involved in regulation of B cell activation and survival. The cytoplasmic domain regions are serine and threonine rich and contain multiple phosphorylation consensus sequences.

BD Pharmingen™ Purified Mouse Anti-Human CD20 - Purified - Clone H1 (also known as FB1) - Isotype Mouse IgG2a, κ - Reactivity Hu - 0.1 mg

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Immunogen: Human B lymphoma cell line

Isotype: IgG2a kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store undiluted at 4°C.

Target Details for CD20

Target: CD20 (MS4A1) (Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1))

Alternative Name: CD20

Background: Synonyms: Cytoplasmic domain