Fc gamma RII (CD32) antibody

Catalog No. ABIN2689189

This anti- antibody is a Mouse Monoclonal antibody detecting in FACS. Suitable for Human, Rhesus Monkey, Baboon and Cynomolgus. This Primary Antibody has been cited in 1 publication.

Quick Overview for Fc gamma RII (CD32) antibody (ABIN2689189)

Target: Fc gamma RII (CD32)

Reactivity: Human, Rhesus Monkey, Baboon, Cynomolgus

Host: Mouse

Clonality: Monoclonal

Conjugate: Un-conjugated

Application: Flow Cytometry (FACS)

Clone: FLI8-26

Product Details

Brand: BD Pharmingen™

Characteristics: Reacts with the 40 kDa type I membrane glycoprotein, FcγRII, the low affinity receptor for aggregated IgG expressed on B cells, monocytes, granulocytes, and platelets. CD32 mediates endocytosis, cytotoxicity, platelet activation and immunomodulation. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature. Profile of peripheral blood lymphocytes analyzed on a FACScan Profile of peripheral blood monocytes analyzed on a FACScan Profile of peripheral blood granulocytes analyzed on a FACScan

BD Pharmingen™ Purified Mouse Anti-Human CD32 - Purified - Clone FLI8.26 (2003) - Isotype Mouse IgG2b, κ - Reactivity Hu, Bab, Cyno, Rhe - 0.1 mg

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Isotype: IgG2b kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store undiluted at 4°C.

References

Tomiyama, Kunicki, Zipf, Ford, Aster: "Response of human platelets to activating monoclonal antibodies: importance of Fc gamma RII (CD32) phenotype and level of expression." in: Blood, Vol. 80, Issue 9, pp. 2261-8, (1992) (PubMed).

Target Details

Target: Fc gamma RII (CD32)

Alternative Name: CD32

Background: Synonyms: FcγRII