ITGA2 antibody

Catalog No. ABIN2689300

This anti-ITGA2 antibody is a Mouse Monoclonal antibody detecting ITGA2 in FACS and FM. Suitable for Human. This Primary Antibody has been cited in 1 publication.

Quick Overview for ITGA2 antibody (ABIN2689300)

Target: ITGA2 (Integrin alpha 2 (ITGA2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ITGA2 antibody is un-conjugated

Application: Flow Cytometry (FACS), Fluorescence Microscopy (FM)

Clone: 12F1

Product Details anti-ITGA2 Antibody

Characteristics: Reacts with integrin α2 chain (VLA-α2), a member of the integrin family of extracellular matrix and cell-cell adhesion receptors. VLA-α2 is non-covalently associated with VLA-β1 chain (CD29) in the VLA-2 complex. α2 is expressed on numerous cell types including activated T cells, platelets, and long-term cultivated T cells. α2β1 is a well-established receptor for collagen. This antibody is useful for studies of integrin expression and function. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature. Profile of peripheral blood platelets analyzed by flow cytometry

BD Pharmingen™ Purified Mouse Anti-Human CD49b - Purified - Clone 12F1 - Isotype Mouse IgG2a, κ - Reactivity Hu - 0.1 mg

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Isotype: IgG2a kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store undiluted at 4°C.

References for anti-ITGA2 antibody (ABIN2689300)

Hemler: "VLA proteins in the integrin family: structures, functions, and their role on leukocytes." in: Annual review of immunology, Vol. 8, pp. 365-400, (1990) (PubMed).

Target Details for ITGA2

Target: ITGA2 (Integrin alpha 2 (ITGA2))

Alternative Name: CD49b

Background: Synonyms: Integrin α2 chain

Pathways: CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Integrin Complex