CD56 antibody

Catalog No. ABIN2689340

This Mouse Monoclonal antibody specifically detects CD56 in FACS, ELISA, IP, IHC (fro) and Func. It exhibits reactivity toward Human and has been mentioned in 12+ publications.

Quick Overview for CD56 antibody (ABIN2689340)

Target: CD56 (NCAM1) (Neural Cell Adhesion Molecule 1 (NCAM1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD56 antibody is un-conjugated

Application: Flow Cytometry (FACS), ELISA, Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)

Clone: NCAM16-2

Product Details anti-CD56 Antibody

Brand: BD Pharmingen™

Characteristics: Anti-N-CAM-16 monoclonal antibody (clone NCAM16.2) CAMFolio™ recognizes the third extracellular immunoglobulin-like domain common to three molecular weight forms (120-, 140-, and 180-kD) of the neural cell adhesion molecule (N-CAM). The N-CAM glycoprotein is expressed on many different cell and tissue types including natural killer (NK) lymphocytes, a subset of T lymphocytes and interleukin-2 (IL-2)-activated thymocytes, and neural, neuroendocrine, and degenerating of diseased muscle tissue.

BD Pharmingen™ Purified Mouse Anti-Human CD56 - Purified - Clone NCAM16.2 (also known as NCAM 16) - Isotype Mouse IgG2b, κ - Reactivity Hu - 0.2 mg

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Isotype: IgG2b kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store undiluted at 4°C.

References for anti-CD56 antibody (ABIN2689340)

Zocchi, Vidal, Poggi: "Involvement of CD56/N-CAM molecule in the adhesion of human solid tumor cell lines to endothelial cells." in: Experimental cell research, Vol. 204, Issue 1, pp. 130-5, (1993) (PubMed).

Birdsall, Lane, Ramser, Anderson: "Induction of VCAM-1 and ICAM-1 on human neural cells and mechanisms of mononuclear leukocyte adherence." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 148, Issue 9, pp. 2717-23, (1992) (PubMed).

Doherty, Ashton, Moore, Walsh: "Morphoregulatory activities of NCAM and N-cadherin can be accounted for by G protein-dependent activation of L- and N-type neuronal Ca2+ channels." in: Cell, Vol. 67, Issue 1, pp. 21-33, (1991) (PubMed).

Jin, Hemperly, Lloyd: "Expression of neural cell adhesion molecule in normal and neoplastic human neuroendocrine tissues." in: The American journal of pathology, Vol. 138, Issue 4, pp. 961-9, (1991) (PubMed).

Lanier, Chang, Azuma, Ruitenberg, Hemperly, Phillips: "Molecular and functional analysis of human natural killer cell-associated neural cell adhesion molecule (N-CAM/CD56)." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 146, Issue 12, pp. 4421-6, (1991) (PubMed).

Schubert, Zimmermann, Cramer, Starzinski-Powitz: "Lymphocyte antigen Leu-19 as a molecular marker of regeneration in human skeletal muscle." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 86, Issue 1, pp. 307-11, (1989) (PubMed).

Lanier, Testi, Bindl, Phillips: "Identity of Leu-19 (CD56) leukocyte differentiation antigen and neural cell adhesion molecule." in: The Journal of experimental medicine, Vol. 169, Issue 6, pp. 2233-8, (1989) (PubMed).

Edelman: "Cell adhesion molecules in the regulation of animal form and tissue pattern." in: Annual review of cell biology, Vol. 2, pp. 81-116, (1987) (PubMed).

Lanier, Le, Ding, Evans, Krensky, Clayberger, Phillips: "Expression of Leu-19 (NKH-1) antigen on IL 2-dependent cytotoxic and non-cytotoxic T cell lines." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 138, Issue 7, pp. 2019-23, (1987) (PubMed).

Cunningham, Hemperly, Murray, Prediger, Brackenbury, Edelman: "Neural cell adhesion molecule: structure, immunoglobulin-like domains, cell surface modulation, and alternative RNA splicing." in: Science (New York, N.Y.), Vol. 236, Issue 4803, pp. 799-806, (1987) (PubMed).

Hemperly, Murray, Edelman, Cunningham: "Sequence of a cDNA clone encoding the polysialic acid-rich and cytoplasmic domains of the neural cell adhesion molecule N-CAM." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 83, Issue 9, pp. 3037-41, (1986) (PubMed).

Lanier, Le, Civin, Loken, Phillips: "The relationship of CD16 (Leu-11) and Leu-19 (NKH-1) antigen expression on human peripheral blood NK cells and cytotoxic T lymphocytes." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 136, Issue 12, pp. 4480-6, (1986) (PubMed).

Target Details for CD56

Target: CD56 (NCAM1) (Neural Cell Adhesion Molecule 1 (NCAM1))

Alternative Name: CD56

Background: Synonyms: N-CAM