CEACAM8 antibody

Catalog No. ABIN2689375

Cited in 1 publication. The Mouse Monoclonal anti-CEACAM8 antibody (Clone G10F5) (ABIN2689375) specifically detects CEACAM8 in FACS and FM. The antibody is reactive with Human samples.

Quick Overview for CEACAM8 antibody (ABIN2689375)

Target: CEACAM8 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 8 (CEACAM8))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CEACAM8 antibody is un-conjugated

Application: Flow Cytometry (FACS), Fluorescence Microscopy (FM)

Clone: G10F5

Product Details anti-CEACAM8 Antibody

Characteristics: Reacts with CD66b, a glycosylphosphatidylinositol (GPI) linked protein with a molecular weight of 100 kD expressed on granulocytes. This molecule was previously clustered as CD67 in the Fourth Human Leucocyte Differentiation Antigen (HLDA) Workshop and renamed CD66b in the Fifth HLDA Workshop. CD66b is a member of the carcinoembryonic antigen (CEA)-like glycoprotein family present on granulocytes and referred to as non-specific cross-reacting antigens (NCA). Granulocyte activation induced with soluble stimulators (calcium ionophore, phorbol myristate acetate, Nformylmethionyl- leucyl-phenylalanine) results in release and increased expression of NCA. Findings suggest that these molecules may play a role in phagocytosis, chemotaxis and adherence. Profile of peripheral blood lymphocytes analyzed on a FACScan

BD Pharmingen™ Purified Mouse Anti-Human CD66b - Purified - Clone G10F5 - Isotype Mouse IgM, κ - Reactivity Hu - 0.1 mg

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Isotype: IgM kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store undiluted at 4°C.

References for anti-CEACAM8 antibody (ABIN2689375)

Lund-Johansen, Olweus, Horejsi, Skubitz, Thompson, Vilella, Symington: "Activation of human phagocytes through carbohydrate antigens (CD15, sialyl-CD15, CDw17, and CDw65)." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 148, Issue 10, pp. 3221-9, (1992) (PubMed).

Target Details for CEACAM8

Target: CEACAM8 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 8 (CEACAM8))

Alternative Name: CD66b