CD68 antibody

Catalog No. ABIN2689378

This anti-CD68 antibody is a Mouse Monoclonal antibody detecting CD68 in IHC (fro) and ICS. Suitable for Human. This Primary Antibody has been cited in 2+ publications.

Quick Overview for CD68 antibody (ABIN2689378)

Target: CD68 (CD68 Molecule (CD68))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD68 antibody is un-conjugated

Application: Immunohistochemistry (Frozen Sections) (IHC (fro)), Intracellular Staining (ICS)

Clone: Y1-82A

Product Details anti-CD68 Antibody

Brand: BD Pharmingen™

Characteristics: Reacts with a 110 kDa-type I-transmembrane glycoprotein expressed in cytoplasmic granules of monocytes/ macrophages, dendritic cells, granulocytes, myeloid progenitor cells and, reportedly, a subset of CD34-positive hemopoietic bone marrow progenitor cells. CD68 belongs to the sialomucin family and its function has not been fully elucidated. This antibody could be useful in studies of myeloid cell development. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature. Profile of CD68 expressed on permeabilized peripheral blood mononuclear cell (monocytes) analyzed on a FACScan

BD Pharmingen™ Purified Mouse Anti-Human CD68 - Purified - Clone Y1/82A - Isotype Mouse IgG2b, κ - Reactivity Hu - 0.1 mg

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Isotype: IgG2b kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store undiluted at 4°C.

References for anti-CD68 antibody (ABIN2689378)

Davey, Erber, Gatter, Mason: "The use of monoclonal antibody Y1/82A in the identification of acute myeloblastic and monocytic leukemias." in: American journal of clinical pathology, Vol. 89, Issue 1, pp. 76-80, (1988) (PubMed).

Davey, Cordell, Erber, Pulford, Gatter, Mason: "Monoclonal antibody (Y1/82A) with specificity towards peripheral blood monocytes and tissue macrophages." in: Journal of clinical pathology, Vol. 41, Issue 7, pp. 753-8, (1988) (PubMed).

Target Details for CD68

Target: CD68 (CD68 Molecule (CD68))

Alternative Name: CD68