CCL2 antibody

Catalog No. ABIN2689837

This anti-CCL2 antibody is a Mouse Monoclonal antibody detecting CCL2 in ELISA, Neut and Inhibition. Suitable for Human. This Primary Antibody has been cited in 3+ publications.

Quick Overview for CCL2 antibody (ABIN2689837)

Target: CCL2 (Chemokine (C-C Motif) Ligand 2 (CCL2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CCL2 antibody is un-conjugated

Application: ELISA, Neutralization (Neut), Blocking Antibody (Inhibition)

Clone: 5D3

Product Details anti-CCL2 Antibody

Brand: BD Pharmingen™

Characteristics: The 5D3-F7 antibody reacts with human monocyte chemoattractant protein-1 (MCP-1), also known as monocyte chemotactic and activating factor (MCAF).

BD Pharmingen™ Purified Mouse Anti-Human MCP-1 - Purified - Clone 5D3-F7 - Isotype Mouse IgG1, κ - Reactivity Hu - 1 mg

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Immunogen: Recombinant Human MCP-1

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store undiluted at 4°C.

References for anti-CCL2 antibody (ABIN2689837)

Prussin, Metcalfe: "Detection of intracytoplasmic cytokine using flow cytometry and directly conjugated anti-cytokine antibodies." in: Journal of immunological methods, Vol. 188, Issue 1, pp. 117-28, (1996) (PubMed).

Peri, Milanese, Matteucci, Ruco, Zhou, Sozzani, Coletta, Mantovani: "A new monoclonal antibody (5D3-F7) which recognizes human monocyte-chemotactic protein-1 but not related chemokines. Development of a sandwich ELISA and in situ detection of producing cells." in: Journal of immunological methods, Vol. 174, Issue 1-2, pp. 249-57, (1994) (PubMed).

Rollins, Stier, Ernst, Wong: "The human homolog of the JE gene encodes a monocyte secretory protein." in: Molecular and cellular biology, Vol. 9, Issue 11, pp. 4687-95, (1990) (PubMed).

Target Details for CCL2

Target: CCL2 (Chemokine (C-C Motif) Ligand 2 (CCL2))

Alternative Name: MCP-1

Pathways: Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, ER-Nucleus Signaling, Unfolded Protein Response, The Global Phosphorylation Landscape of SARS-CoV-2 Infection