Myeloperoxidase antibody

Catalog No. ABIN2689854

The Mouse Monoclonal anti-Myeloperoxidase antibody has been validated for IHC (fro), IHC (f), IHC (zinc) and ICS. It is suitable to detect Myeloperoxidase in samples from Human. There is 1 publication available.

Quick Overview for Myeloperoxidase antibody (ABIN2689854)

Target: Myeloperoxidase (MPO)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Myeloperoxidase antibody is un-conjugated

Application: Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Immunohistochemistry (Zinc-fixed Sections) (IHC (zinc)), Intracellular Staining (ICS)

Clone: 1B10

Product Details anti-Myeloperoxidase Antibody

Brand: BD Pharmingen™

Characteristics: Reacts with myeloperoxidase (MPO), a hemoprotein of 140 kDa, composed of two heavy subunits of 52 kDa and two light chains of 15 kDa. MPO is stored in primary azurophilic granules of neutrophils and plays a major role in the bactericidal activity of neutrophils during phagocytosis. It catalyzes the generation of hypochlorous acid, a powerful oxidant. 1B10 antibody detects MPO in neutrophils, monocytes and HL-60 cells. This reagent is suitable for immunohistochemical staining of acetone-fixed, frozen tissue section, or formalin-fixed, paraffin-embedded tissue sections with TUF pretreatment, or zinc-fixed, paraffin-embedded tissue sections with no pretreatment.

BD Pharmingen™ Purified Mouse Anti-Human Myeloperoxidase - Purified - Clone 1B10 - Isotype Mouse IgG1, κ - Reactivity Hu - 0.1 mg

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store undiluted at 4°C.

References for anti-Myeloperoxidase antibody (ABIN2689854)

Audrain, Baranger, Moguilevski, Martin, Devys, Lockwood, Muller, Esnault: "Anti-native and recombinant myeloperoxidase monoclonals and human autoantibodies." in: Clinical and experimental immunology, Vol. 107, Issue 1, pp. 127-34, (1997) (PubMed).

Target Details for Myeloperoxidase

Target: Myeloperoxidase (MPO)

Alternative Name: Myeloperoxidase

Background: Synonyms: MPO

Pathways: Chromatin Binding