FAIM3 antibody (AA 51-150) (HRP)

Catalog No. ABIN2689989

This anti-FAIM3 antibody is a Rabbit Polyclonal antibody detecting FAIM3 in WB, ELISA, IHC (p) and IHC (fro). Suitable for Human.

Quick Overview for FAIM3 antibody (AA 51-150) (HRP) (ABIN2689989)

Target: FAIM3 (Fas Apoptotic Inhibitory Molecule 3 (FAIM3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FAIM3 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-FAIM3 Antibody (HRP)

Binding Specificity: AA 51-150

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FAIM3

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for FAIM3

Target: FAIM3 (Fas Apoptotic Inhibitory Molecule 3 (FAIM3))

Alternative Name: FAIM3

Background:

Synonyms: TOSO, FAIM3, Fas apoptotic inhibitory molecule 3, Regulator of Fas-induced apoptosis Toso

Background: May play a role in the immune system processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Seems to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, rather than blocking apoptotic signals downstream. May inhibit FAS-induced apoptosis by preventing CASP8 processing through CFLAR up-regulation.

Gene ID: 9214

UniProt: O60667