ADH1B antibody

Catalog No. ABIN2715877

The Mouse Monoclonal anti-ADH1B antibody has been validated for WB, IHC, IF and FACS. It is suitable to detect ADH1B in samples from Human, Rat and Dog. There is 1 publication available.

Quick Overview for ADH1B antibody (ABIN2715877)

Target: ADH1B (Alcohol Dehydrogenase 1B (Class I), beta Polypeptide (ADH1B))

Reactivity: Human, Rat, Dog

Host: Mouse

Clonality: Monoclonal

Conjugate: This ADH1B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: 4F12

Product Details anti-ADH1B Antibody

Characteristics: Homo sapiens alcohol dehydrogenase 1B (class I), beta polypeptide (ADH1B)

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogen: Full length human recombinant protein of human ADH1B (NP_000659) produced in HEK293T cell.

Isotype: IgG2a

Application Details

Application Notes: WB 1:500, IHC 1:150, IF 1:100, FLOW 1:100

Comment:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

References for anti-ADH1B antibody (ABIN2715877)

Samak, Gangwar, Meena, Rao, Shukla, Manda, Narayanan, Jaggar, Rao: "Calcium Channels and Oxidative Stress Mediate a Synergistic Disruption of Tight Junctions by Ethanol and Acetaldehyde in Caco-2 Cell Monolayers." in: Scientific reports, Vol. 6, pp. 38899, (2018) (PubMed).

Target Details for ADH1B

Target: ADH1B (Alcohol Dehydrogenase 1B (Class I), beta Polypeptide (ADH1B))

Alternative Name: ADH1B

Background: The protein encoded by this gene is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. This encoded protein, consisting of several homo- and heterodimers of alpha, beta, and gamma subunits, exhibits high activity for ethanol oxidation and plays a major role in ethanol catabolism. Three genes encoding alpha, beta and gamma subunits are tandemly organized in a genomic segment as a gene cluster.

Molecular Weight: 39.7 kDa

Gene ID: 125

NCBI Accession: NM_000668

HGNC: 125