alpha Fetoprotein antibody

Catalog No. ABIN2716002

The Mouse Monoclonal anti-alpha Fetoprotein antibody has been validated for WB and FACS. It is suitable to detect alpha Fetoprotein in samples from Human.

Quick Overview for alpha Fetoprotein antibody (ABIN2716002)

Target: alpha Fetoprotein (AFP) (alpha-Fetoprotein (AFP))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This alpha Fetoprotein antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Clone: 1B3

Product Details anti-alpha Fetoprotein Antibody

Characteristics: Homo sapiens alpha-fetoprotein (AFP)

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogen: Full length human recombinant protein of human AFP(NP_001125) produced in HEK293T cell.

Isotype: IgG1

Application Details

Application Notes: WB 1:500~2000, FLOW 1:100,

Comment:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for alpha Fetoprotein

Target: alpha Fetoprotein (AFP) (alpha-Fetoprotein (AFP))

Alternative Name: AFP

Background: This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.

Molecular Weight: 66.3 kDa

Gene ID: 174

NCBI Accession: NM_001134

HGNC: 174

Pathways: C21-Steroid Hormone Metabolic Process