Dystrobrevin beta antibody

Catalog No. ABIN2719792

The Mouse Monoclonal anti-Dystrobrevin beta antibody has been validated for WB, IHC and FACS. It is suitable to detect Dystrobrevin beta in samples from Human.

Quick Overview for Dystrobrevin beta antibody (ABIN2719792)

Target: Dystrobrevin beta (DTNB) (Dystrobrevin, beta (DTNB))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Dystrobrevin beta antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Clone: 2E6

Product Details anti-Dystrobrevin beta Antibody

Characteristics: Homo sapiens dystrobrevin, beta (DTNB), transcript variant 5

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogen: Full length human recombinant protein of human DTNB(NP_899205) produced in HEK293T cell.

Isotype: IgG1

Application Details

Application Notes: WB 1:1000, IHC 1:150, FLOW 1:100,

Comment:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for Dystrobrevin beta

Target: Dystrobrevin beta (DTNB) (Dystrobrevin, beta (DTNB))

Alternative Name: DTNB

Background: This gene encodes dystrobrevin beta, a component of the dystrophin-associated protein complex (DPC). The DPC consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and dystrobrevin alpha and beta. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Dystrobrevin beta is thought to interact with syntrophin and the DP71 short form of dystrophin. Alternatively spliced transcript variants encoding different isoforms have been identified.

Molecular Weight: 63.6 kDa

Gene ID: 1838

NCBI Accession: NM_183361

HGNC: 1838