PDE6G antibody

Catalog No. ABIN2728523

The Mouse Monoclonal anti-PDE6G antibody has been validated for WB and IHC. It is suitable to detect PDE6G in samples from Human.

Quick Overview for PDE6G antibody (ABIN2728523)

Target: PDE6G (phosphodiesterase 6G, CGMP-Specific, Rod, gamma (PDE6G))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PDE6G antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: 2F5

Product Details anti-PDE6G Antibody

Characteristics: Homo sapiens phosphodiesterase 6G, cGMP-specific, rod, gamma (PDE6G), transcript variant 1

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogen: Full length human recombinant protein of human PDE6G(NP_002593) produced in HEK293T cell.

Isotype: IgG2b

Application Details

Application Notes: WB 1:2000, IHC 1:150,

Comment:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for PDE6G

Target: PDE6G (phosphodiesterase 6G, CGMP-Specific, Rod, gamma (PDE6G))

Alternative Name: PDE6G

Background: This gene encodes the gamma subunit of cyclic GMP-phosphodiesterase, which is composed of alpha- and beta- catalytic subunits and two identical, inhibitory gamma subunits. This gene is expressed in rod photoreceptors and functions in the phototransduction signaling cascade. It is also expressed in a variety of other tissues, and has been shown to regulate the c-Src protein kinase and G-protein-coupled receptor kinase 2. Alternative splicing results in multiple transcript variants.

Molecular Weight: 9.5 kDa

Gene ID: 5148

NCBI Accession: NM_002602

HGNC: 5148

Pathways: EGFR Signaling Pathway, Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction