PNPO antibody

Catalog No. ABIN2729267

Product Details anti-PNPO Antibody

Target: PNPO (Pyridoxamine 5'-Phosphate Oxidase (PNPO))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PNPO antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Characteristics: Homo sapiens pyridoxamine 5'-phosphate oxidase (PNPO)

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogen: Full length human recombinant protein of human PNPO(NP_060599) produced in HEK293T cell.

Clone: 1H9

Isotype: IgG2b

Application Details

Application Notes: WB 1:500, IHC 1:150,

Comment:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for PNPO

Target: PNPO (Pyridoxamine 5'-Phosphate Oxidase (PNPO))

Alternative Name: PNPO (PNPO Products)

Synonyms: im:7138360 antibody, ECK1634 antibody, JW1630 antibody, PDXPO antibody, AI415282 antibody, pyridoxamine 5'-phosphate oxidase antibody, pyridoxine 5'-phosphate oxidase antibody, Pyridoxamine 5'-phosphate oxidase antibody, pnpo antibody, pdxH antibody, Mrub_2888 antibody, Arnit_1624 antibody, Ndas_4168 antibody, Mesil_2817 antibody, Isop_0296 antibody, Despr_1960 antibody, Pedsa_1348 antibody, Mesop_5639 antibody, PNPO antibody, Pnpo antibody

Background: The enzyme encoded by this gene catalyzes the terminal, rate-limiting step in the synthesis of pyridoxal 5'-phosphate, also known as vitamin B6. Vitamin B6 is a required co-factor for enzymes involved in both homocysteine metabolism and synthesis of neurotransmitters such as catecholamine. Mutations in this gene result in pyridoxamine 5'-phosphate oxidase (PNPO) deficiency, a form of neonatal epileptic encephalopathy. COMPLETENESS: complete on the 3' end.

Molecular Weight: 29.8 kDa

Gene ID: 55163

NCBI Accession: NM_018129

HGNC: 55163