SAMHD1 antibody

Catalog No. ABIN2731375

Cited in 1 publication. The Mouse Monoclonal anti-SAMHD1 antibody (Clone 2B5) (ABIN2731375) specifically detects SAMHD1 in WB, IF and FACS. The antibody is reactive with Human samples.

Quick Overview for SAMHD1 antibody (ABIN2731375)

Target: SAMHD1 (SAM Domain and HD Domain 1 (SAMHD1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SAMHD1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: 2B5

Product Details anti-SAMHD1 Antibody

Characteristics: Homo sapiens SAM domain and HD domain 1 (SAMHD1)

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogen: Full length human recombinant protein of human SAMHD1 (NP_056289) produced in HEK293T cell.

Isotype: IgG2b

Application Details

Application Notes: WB 1:500~2000, IF 1:100, FLOW 1:100,

Comment:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

References for anti-SAMHD1 antibody (ABIN2731375)

Hu, Li, Xu, Mei, Le Duff, Yin, Pang, Cen, Jin, Liang, Guo: "SAMHD1 Inhibits LINE-1 Retrotransposition by Promoting Stress Granule Formation." in: PLoS genetics, Vol. 11, Issue 7, pp. e1005367, (2015) (PubMed).

Target Details for SAMHD1

Target: SAMHD1 (SAM Domain and HD Domain 1 (SAMHD1))

Alternative Name: SAMHD1

Background: This gene may play a role in regulation of the innate immune response. The encoded protein is upregulated in response to viral infection and may be involved in mediation of tumor necrosis factor-alpha proinflammatory responses. Mutations in this gene have been associated with Aicardi-Goutieres syndrome. COMPLETENESS: complete on the 3' end.

Molecular Weight: 72 kDa

Gene ID: 25939

NCBI Accession: NM_015474

HGNC: 25939