SNAP25 antibody
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- Target See all SNAP25 Antibodies
- SNAP25 (Synaptosomal-Associated Protein, 25kDa (SNAP25))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This SNAP25 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)
- Characteristics
- Homo sapiens synaptosomal-associated protein, 25 kDa (SNAP25), transcript variant 1
- Purification
- Purified from mouse ascites fluids by affinity chromatography
- Immunogen
- Full length human recombinant protein of human SNAP25 (NP_003072) produced in HEK293T cell.
- Clone
- 4B5
- Isotype
- IgG2a
- Top Product
- Discover our top product SNAP25 Primary Antibody
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- Application Notes
- WB 1:2000, IHC 1:150, IF 1:100, FLOW 1:100
- Comment
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The concentration of the product may vary between diferrent lots.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5-1.0 mg/mL
- Buffer
- PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
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- Target
- SNAP25 (Synaptosomal-Associated Protein, 25kDa (SNAP25))
- Alternative Name
- SNAP25 (SNAP25 Products)
- Background
- Synaptic vesicle membrane docking and fusion is mediated by SNAREs (soluble N-ethylmaleimide-sensitive factor attachment protein receptors) located on the vesicle membrane (v-SNAREs) and the target membrane (t-SNAREs). The assembled v-SNARE/t-SNARE complex consists of a bundle of four helices, one of which is supplied by v-SNARE and the other three by t-SNARE. For t-SNAREs on the plasma membrane, the protein syntaxin supplies one helix and the protein encoded by this gene contributes the other two. Therefore, this gene product is a presynaptic plasma membrane protein involved in the regulation of neurotransmitter release. Two alternative transcript variants encoding different protein isoforms have been described for this gene.
- Molecular Weight
- 23.2 kDa
- Gene ID
- 6616
- NCBI Accession
- NM_003081
- HGNC
- 6616
- Pathways
- Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
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