TULP3 antibody
Quick Overview for TULP3 antibody (ABIN2734599)
Target
See all TULP3 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Characteristics
- Homo sapiens tubby like protein 3 (TULP3), transcript variant 1
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Purification
- Purified from mouse ascites fluids by affinity chromatography
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Immunogen
- Full length human recombinant protein of human TULP3(NP_003315) produced in HEK293T cell.
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Isotype
- IgG2b
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Application Notes
- WB 1:2000, IF 1:100,
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Comment
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The concentration of the product may vary between diferrent lots.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5-1.0 mg/mL
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Buffer
- PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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- TULP3 (Tubby Like Protein 3 (TULP3))
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Alternative Name
- TULP3
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Background
- This gene encodes a member of the tubby gene family of bipartite transcription factors. Members of this family have been identified in plants, vertebrates, and invertebrates, and they share a conserved N-terminal transcription activation region and a conserved C-terminal DNA and phosphatidylinositol-phosphate binding region. The encoded protein binds to phosphoinositides in the plasma membrane via its C-terminal region and probably functions as a membrane-bound transcription regulator that translocates to the nucleus in response to phosphoinositide hydrolysis, for instance, induced by G-protein-coupled-receptor signaling. It plays an important role in neuronal development and function. Two transcript variants encoding distinct isoforms have been identified for this gene.
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Molecular Weight
- 49.5 kDa
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Gene ID
- 7289
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NCBI Accession
- NM_003324
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HGNC
- 7289
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Pathways
- Regulation of G-Protein Coupled Receptor Protein Signaling, Tube Formation
Target
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