VEGF antibody (AA 27-233)

Catalog No. ABIN2735205

The Mouse Monoclonal anti-VEGF antibody has been validated for WB and IHC. It is suitable to detect VEGF in samples from Human and Dog. There are 2+ publications available.

Quick Overview for VEGF antibody (AA 27-233) (ABIN2735205)

Target: VEGF (Vascular Endothelial Growth Factor (VEGF))

Reactivity: Human, Dog

Host: Mouse

Clonality: Monoclonal

Conjugate: This VEGF antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: 4G3

Product Details anti-VEGF Antibody

Binding Specificity: AA 27-233

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogen: Human recombinant protein fragment corresponding to amino acids 27-233 of human VEGFA (NP_003367) produced in E.coli.

Isotype: IgG2b

Application Details

Application Notes: WB 1:2500~5000, IHC: 1:50-1:150,

Comment:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS ( pH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

References for anti-VEGF antibody (ABIN2735205)

Chen, Tang, Feng, Li, Xiang, He, Ren, Peng, Xiang: "ADAMTS9 is Silenced by Epigenetic Disruption in Colorectal Cancer and Inhibits Cell Growth and Metastasis by Regulating Akt/p53 Signaling." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 44, Issue 4, pp. 1370-1380, (2018) (PubMed).

Shao, Feng, Zhang, Yu, Li, Tan, Xu, Ying, Li, Yang, Peng, Tang, Li, Ren, Tao, Xiang: "The 3p14.2 tumour suppressor ADAMTS9 is inactivated by promoter CpG methylation and inhibits tumour cell growth in breast cancer." in: Journal of cellular and molecular medicine, Vol. 22, Issue 2, pp. 1257-1271, (2018) (PubMed).

Target Details for VEGF

Target: VEGF (Vascular Endothelial Growth Factor (VEGF))

Alternative Name: VEGF

Molecular Weight: 23.8 kDa

Gene ID: 7422

NCBI Accession: NM_001025366

HGNC: 7422