CD147 antibody

Catalog No. ABIN2738484

The Mouse Monoclonal anti-CD147 antibody has been validated for WB, FACS, IHC, IF, IP, IHC (p) and Func. It is suitable to detect CD147 in samples from Human.

Quick Overview for CD147 antibody (ABIN2738484)

Target: CD147 (BSG) (Basigin (Ok Blood Group) (BSG))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD147 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Functional Studies (Func)

Clone: 8D6

Product Details anti-CD147 Antibody

Specificity: Human Basigin / Emmprin / CD147

Purification: Protein G purified

Immunogen: Human T cell line Molt-13.

Type of Immunogen: Cells

Isotype: IgG1

Application Details

Application Notes: Approved: Flo (0.5 - 1 μg/10 x10⁶), Func, IF (1:100 - 1:200), IHC, IHC-P (1 - 2 μg/mL), IP, WB (0.5 - 1 μg/mL)

Usage: This antibody recognizes extracellular epitope 2 within the N-terminal Ig domain of human CD147. It expressed more intensely on thymocytes than on mature peripheral blood T cells. CD147 is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. CD147 stimulates the production of interstitial collagenase, gelatinase A, stromelysin-1 and various metalloproteinases (MMPs) by fibroblasts. These enzymes are important factors in cancer invasion and metastasis.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4, 0.1 mg/mL BSA, 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2°C to 8°C.

Target Details for CD147

Target: CD147 (BSG) (Basigin (Ok Blood Group) (BSG))

Alternative Name: Basigin / Emmprin / CD147

Background: Name/Gene ID: BSG

Synonyms: BSG, 5F7, Basigin, Basigin (Ok blood group), CD147 antigen, Collagenase stimulatory factor, EMMPRIN, OK, OK blood group antigen, TCSF, CD147, M6

Gene ID: 682

Pathways: S100 Proteins