BCL2L1 antibody

Catalog No. ABIN2738536

This anti-BCL2L1 antibody is a Mouse Monoclonal antibody detecting BCL2L1 in WB, IHC, ELISA, IF, FACS, IP and IHC (p). Suitable for Human, Mouse, Rat, Pig, Sheep, Dog, Cow, Monkey, Horse, Hamster and Chimpanzee.

Quick Overview for BCL2L1 antibody (ABIN2738536)

Target: BCL2L1 (BCL2-Like 1 (BCL2L1))

Reactivity: Human, Mouse, Rat, Pig, Sheep, Dog, Cow, Monkey, Horse, Hamster, Chimpanzee

Host: Mouse

Clonality: Monoclonal

Conjugate: This BCL2L1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: BX006

Product Details anti-BCL2L1 Antibody

Specificity: Human BCL2L1 / Bcl-xL

Purification: Protein G purified

Immunogen: Amino acids QSNRELVVDFLS (3-14) of the human protein were used as the immunogen for this Bcl-X antibody (2). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Baboon, Monkey, Marmoset, Mouse, Rat, Ferret, Sheep, Cat, Bovine, Hamster, Elephant, Horse, Pig, Dog (100%), Galago (92%).

Type of Immunogen: Synthetic peptide

Isotype: IgG2a

Application Details

Application Notes: Approved: ELISA, Flo (0.5 - 1 μg/10 x10⁶), IF (1 - 2 μg/mL), IHC, IHC-P (0.5 - 1 μg/mL), IP, WB (0.5 - 1 μg/mL)

Usage: This antibody recognizes a protein of 27  kDa, identified as Bcl-X. The mAb shows no cross-reaction with Bcl2 alpha or Bax. Bcl-X has two isoforms, XL (long), a 241 amino acid protein which suppresses cell death, and XS (short), a 178 amino acid protein lacking a 63 amino acid domain which functions as a dominant inhibitor of Bcl2. ELISA: Order BSA-free format for coating.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4, 0.1 mg/mL BSA, 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2°C to 8°C.

Target Details for BCL2L1

Target: BCL2L1 (BCL2-Like 1 (BCL2L1))

Alternative Name: BCL2L1 / BCL-XL

Background: Name/Gene ID: BCL2L1
Family: Apoptosis

Synonyms: BCL2L1, Apoptosis regulator Bcl-X, Bcl-xL, BCL-XL/S, BCLXS, Bcl-2-like protein 1, BCL2-like 1, BCL2L, Bcl-X, Bcl-xS, BCLXL, PPP1R52, Bcl2-L-1, BCLX

Gene ID: 598

Pathways: Apoptosis, Negative Regulation of intrinsic apoptotic Signaling