STS antibody (N-Term) (Atto 647N)

Catalog No. ABIN2745511

This anti-STS antibody is a Rabbit Polyclonal antibody detecting STS in IHC and ICC. Suitable for Human and Mouse.

Quick Overview for STS antibody (N-Term) (Atto 647N) (ABIN2745511)

Target: STS (Steroid Sulfatase (STS))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STS antibody is conjugated to Atto 647N

Application: Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Product Details anti-STS Antibody (Atto 647N)

Binding Specificity: N-Term

Specificity: Recognizes human and mouse Asc.

Cross-Reactivity: Human, Mouse (Murine)

Immunogen: Synthetic peptide corresponding to aa at the N-terminal human Asc.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: In PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Short Term Storage: +4°C
Long Term Storage: +4°C
Keep conjugated formats at +4°C. Stable for at least 1 year after receipt when stored at +4°C.

Expiry Date: 12 months

Target Details for STS

Target: STS (Steroid Sulfatase (STS))

Alternative Name: Asc

Background: Asc promotes caspase-mediated apoptosis. This proapoptotic activity is mediated predominantly through the activation of caspase-9. It is a component of the inflammasome, a protein complex which also includes NLRP3/NALP3, CARD8 and CASP1 and whose function is the activation of proinflammatory caspases.

UniProt: Q9ULZ3

Pathways: Steroid Hormone Biosynthesis, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation