ADCY5 antibody

Catalog No. ABIN2746164

There are 3+ publications for this product available. The Rabbit Polyclonal anti-ADCY5 antibody is suitable to detect ADCY5 in samples from Mouse and Rat. It has been validated for WB, ELISA, IHC, IF, ICC and CM.

Quick Overview for ADCY5 antibody (ABIN2746164)

Target: ADCY5 (Adenylate Cyclase 5 (ADCY5))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADCY5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Confocal Microscopy (CM)

Product Details anti-ADCY5 Antibody

Purification: Affinity Purified

Immunogen: Synthetic peptide corresponding to unique amino acid sequence on rat Particulate Adenylyl Cyclase 5 protein.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.75-1.20 μg/μL

References for anti-ADCY5 antibody (ABIN2746164)

Ortiz-Capisano, Ortiz, Harding, Garvin, Beierwaltes: "Adenylyl cyclase isoform v mediates renin release from juxtaglomerular cells." in: Hypertension (Dallas, Tex. : 1979), Vol. 49, Issue 3, pp. 618-24, (2007) (PubMed).

Grünberger, Obermayer, Klar, Kurtz, Schweda: "The calcium paradoxon of renin release: calcium suppresses renin exocytosis by inhibition of calcium-dependent adenylate cyclases AC5 and AC6." in: Circulation research, Vol. 99, Issue 11, pp. 1197-206, (2006) (PubMed).

Kolachala, Asamoah, Wang, Srinivasan, Merlin, Sitaraman: "Interferon-gamma down-regulates adenosine 2b receptor-mediated signaling and short circuit current in the intestinal epithelia by inhibiting the expression of adenylate cyclase." in: The Journal of biological chemistry, Vol. 280, Issue 6, pp. 4048-57, (2005) (PubMed).

Target Details for ADCY5

Target: ADCY5 (Adenylate Cyclase 5 (ADCY5))

Alternative Name: ADCY5

UniProt: Q04400

Pathways: EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma