ADCY5 antibody

Catalog No. ABIN2746164

The Rabbit Polyclonal anti-ADCY5 antibody has been validated for WB, ELISA, IHC, IF, ICC and CM. It is suitable to detect ADCY5 in samples from Mouse and Rat. There are 3+ publications available.

Quick Overview for ADCY5 antibody (ABIN2746164)

Target: ADCY5 (Adenylate Cyclase 5 (ADCY5))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADCY5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Confocal Microscopy (CM)

Product Details anti-ADCY5 Antibody

Purification: Affinity Purified

Immunogen: Synthetic peptide corresponding to unique amino acid sequence on rat Particulate Adenylyl Cyclase 5 protein.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.75-1.20 μg/μL

References for anti-ADCY5 antibody (ABIN2746164)

Ortiz-Capisano, Ortiz, Harding, Garvin, Beierwaltes: "Adenylyl cyclase isoform v mediates renin release from juxtaglomerular cells." in: Hypertension (Dallas, Tex. : 1979), Vol. 49, Issue 3, pp. 618-24, (2007) (PubMed).

Grünberger, Obermayer, Klar, Kurtz, Schweda: "The calcium paradoxon of renin release: calcium suppresses renin exocytosis by inhibition of calcium-dependent adenylate cyclases AC5 and AC6." in: Circulation research, Vol. 99, Issue 11, pp. 1197-206, (2006) (PubMed).

Kolachala, Asamoah, Wang, Srinivasan, Merlin, Sitaraman: "Interferon-gamma down-regulates adenosine 2b receptor-mediated signaling and short circuit current in the intestinal epithelia by inhibiting the expression of adenylate cyclase." in: The Journal of biological chemistry, Vol. 280, Issue 6, pp. 4048-57, (2005) (PubMed).

Target Details for ADCY5

Target: ADCY5 (Adenylate Cyclase 5 (ADCY5))

Alternative Name: ADCY5

UniProt: Q04400

Pathways: EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma