ADCY6 antibody

Catalog No. ABIN2746168

This anti-ADCY6 antibody is a Rabbit Polyclonal antibody detecting ADCY6 in WB, ELISA, IHC, IP, ICC, IF and CM. Suitable for Mouse and Rat. This Primary Antibody has been cited in 4+ publications.

Quick Overview for ADCY6 antibody (ABIN2746168)

Target: ADCY6 (Adenylate Cyclase 6 (ADCY6))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADCY6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunofluorescence (IF), Confocal Microscopy (CM)

Product Details anti-ADCY6 Antibody

Purification: Affinity Purified

Immunogen: Synthetic peptide corresponding to unique amino acid sequence on rat Particulate Adenylyl Cyclase 6 protein.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.6 μg/μL

References for anti-ADCY6 antibody (ABIN2746168)

Desch, Schubert, Schreiber, Mayer, Friedrich, Artunc, Todorov: "PPARgamma-dependent regulation of adenylate cyclase 6 amplifies the stimulatory effect of cAMP on renin gene expression." in: Molecular endocrinology (Baltimore, Md.), Vol. 24, Issue 11, pp. 2139-51, (2011) (PubMed).

Bazhin, Kahnert, Kimpfler, Schadendorf, Umansky: "Distinct metabolism of cyclic adenosine monophosphate in regulatory and helper CD4+ T cells." in: Molecular immunology, Vol. 47, Issue 4, pp. 678-84, (2010) (PubMed).

Grünberger, Obermayer, Klar, Kurtz, Schweda: "The calcium paradoxon of renin release: calcium suppresses renin exocytosis by inhibition of calcium-dependent adenylate cyclases AC5 and AC6." in: Circulation research, Vol. 99, Issue 11, pp. 1197-206, (2006) (PubMed).

Kolachala, Asamoah, Wang, Srinivasan, Merlin, Sitaraman: "Interferon-gamma down-regulates adenosine 2b receptor-mediated signaling and short circuit current in the intestinal epithelia by inhibiting the expression of adenylate cyclase." in: The Journal of biological chemistry, Vol. 280, Issue 6, pp. 4048-57, (2005) (PubMed).

Target Details for ADCY6

Target: ADCY6 (Adenylate Cyclase 6 (ADCY6))

Alternative Name: ADCY6

UniProt: Q03343

Pathways: EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma