PDE11A antibody (C-Term)

Catalog No. ABIN2747057

This Rabbit Polyclonal antibody specifically detects PDE11A in ELISA, WB, IHC, IF, IP, ICC and CM. It exhibits reactivity toward Human, Mouse and Rat and has been mentioned in 7+ publications.

Quick Overview for PDE11A antibody (C-Term) (ABIN2747057)

Target: PDE11A (phosphodiesterase 11A (PDE11A))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDE11A antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC), Confocal Microscopy (CM)

Product Details anti-PDE11A Antibody

Binding Specificity: AA 420-480, C-Term

Purification: Affinity Purified

Immunogen: Synthetic peptide taken within amino acid region 420-480 on PDE11A protein, common to all PDE11A variants.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.69 μg/μL

References for anti-PDE11A antibody (ABIN2747057)

Kelly: "Does phosphodiesterase 11A (PDE11A) hold promise as a future therapeutic target?" in: Current pharmaceutical design, Vol. 21, Issue 3, pp. 389-416, (2015) (PubMed).

Kelly, Adamowicz, Bove, Hartman, Mariga, Pathak, Reinhart, Romegialli, Kleiman: "Select 3',5'-cyclic nucleotide phosphodiesterases exhibit altered expression in the aged rodent brain." in: Cellular signalling, Vol. 26, Issue 2, pp. 383-97, (2014) (PubMed).

Hamilton, Hu, Kolomitro, Bell, Maurice, Graham, Siemens: "Potential therapeutic applications of phosphodiesterase inhibition in prostate cancer." in: World journal of urology, Vol. 31, Issue 2, pp. 325-30, (2013) (PubMed).

Genders, Bradley, Rattigan, Richards: "cGMP phosphodiesterase inhibition improves the vascular and metabolic actions of insulin in skeletal muscle." in: American journal of physiology. Endocrinology and metabolism, Vol. 301, Issue 2, pp. E342-50, (2011) (PubMed).

Kruse, Møller, Tibaek, Gammeltoft, Olesen, Kruuse: "PDE9A, PDE10A, and PDE11A expression in rat trigeminovascular pain signalling system." in: Brain research, Vol. 1281, pp. 25-34, (2009) (PubMed).

Baxendale, Fraser: "Mammalian sperm phosphodiesterases and their involvement in receptor-mediated cell signaling important for capacitation." in: Molecular reproduction and development, Vol. 71, Issue 4, pp. 495-508, (2006) (PubMed).

DAndrea, Qiu, Haynes-Johnson, Bhattacharjee, Kraft, Lundeen: "Expression of PDE11A in normal and malignant human tissues." in: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 53, Issue 7, pp. 895-903, (2005) (PubMed).

Target Details for PDE11A

Target: PDE11A (phosphodiesterase 11A (PDE11A))

Alternative Name: PDE11A

UniProt: Q9HCR9

Pathways: cAMP Metabolic Process