Interferon gamma antibody (Biotin)

Catalog No. ABIN2748944

This Mouse Monoclonal antibody specifically detects Interferon gamma in WB, ELISA, IHC, FACS, ELISpot and Neut. It exhibits reactivity toward Rhesus Monkey and has been mentioned in 3+ publications.

Quick Overview for Interferon gamma antibody (Biotin) (ABIN2748944)

Target: Interferon gamma (IFNG)

Reactivity: Rhesus Monkey

Host: Mouse

Clonality: Monoclonal

Conjugate: This Interferon gamma antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), ELISpot, Neutralization (Neut)

Clone: MD-1

Product Details anti-Interferon gamma Antibody (Biotin)

Cross-Reactivity: Cynomolgus, Human, Chimpanzee

Characteristics: The neutralizing monoclonal antibody to monkey IFN-γ . Further, the antibody has been descripted in immunohistochemical staining of frozen tissues of marmosets and in intracellular flow cytometric analysis . The MD-1 antibody has been reported to cross react with rhesus macaque, pig-tailed macaque, cynomogus monkey, baboon and African green monkey IFN-γ and can be used in Luminex systems (Giavedoni L.D. 2005).

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute with sterile distilled water

Storage: 4 °C

References for anti-Interferon gamma antibody (Biotin) (ABIN2748944)

Varela, Verschoor, Lai, Hughes, Mooj, McKinley, Fitzmaurice, Landskron, Willett, Frost, Bogers, Heeney: "Genetic imprint of vaccination on simian/human immunodeficiency virus type 1 transmitted viral genomes in rhesus macaques." in: PLoS ONE, Vol. 8, Issue 8, pp. e70814, (2014) (PubMed).

Pichyangkul, Gettayacamin, Miller, Lyon, Angov, Tongtawe, Ruble, Heppner, Kester, Ballou, Diggs, Voss, Cohen, Walsh: "Pre-clinical evaluation of the malaria vaccine candidate P. falciparum MSP1(42) formulated with novel adjuvants or with alum." in: Vaccine, Vol. 22, Issue 29-30, pp. 3831-40, (2005) (PubMed).

Giavedoni: "Simultaneous detection of multiple cytokines and chemokines from nonhuman primates using luminex technology." in: Journal of immunological methods, Vol. 301, Issue 1-2, pp. 89-101, (2005) (PubMed).

Target Details for Interferon gamma

Target: Interferon gamma (IFNG)

Alternative Name: IFN-gamma

Gene ID: 3458

NCBI Accession: NP_000610

Pathways: Interferon-gamma Pathway, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagy